Adaptive walks on changing landscapes: Levins’ approach extended
نویسندگان
چکیده
منابع مشابه
Adaptive walks on changing landscapes: Levins' approach extended.
The assumption that trade-offs exist is fundamental in evolutionary theory. Levins (Am. Nat. 96 (1962) 361-372) introduced a widely adopted graphical method for analyzing evolution towards an optimal combination of two quantitative traits, which are traded off. His approach explicitly excluded the possibility of density- and frequency-dependent selection. Here we extend Levins method towards mo...
متن کاملAdaptive walks on time-dependent fitness landscapes.
The idea of adaptive walks on fitness landscapes as a means of studying evolutionary processes on large time scales is extended to fitness landscapes that are slowly changing over time. The influence of ruggedness and of the amount of static fitness contributions is investigated for model landscapes derived from Kauffman's NK landscapes. Depending on the amount of static fitness contributions i...
متن کاملSelection Limits to Adaptive Walks on Correlated Landscapes
Adaptation depends critically on the effects of new mutations and their dependency on the genetic background in which they occur. These two factors can be summarized by the fitness landscape. However, it would require testing all mutations in all backgrounds, making the definition and analysis of fitness landscapes mostly inaccessible. Instead of postulating a particular fitness landscape, we a...
متن کاملPhase transition in random adaptive walks on correlated fitness landscapes.
We study biological evolution on a random fitness landscape where correlations are introduced through a linear fitness gradient of strength c. When selection is strong and mutations rare the dynamics is a directed uphill walk that terminates at a local fitness maximum. We analytically calculate the dependence of the walk length on the genome size L. When the distribution of the random fitness c...
متن کاملSonifying stochastic walks on biomolecular energy landscapes
Translating the complex, multi-dimensional data from simulations of biomolecules to intuitive knowledge is a major challenge in computational chemistry and biology. The so-called “free energy landscape” is amongst the most fundamental concepts used by scientists to understand both static and dynamic properties of biomolecular systems. In this paper we use Markov models to design a strategy for ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Theoretical Population Biology
سال: 2004
ISSN: 0040-5809
DOI: 10.1016/j.tpb.2003.10.001